Organic Chemistry

Chemistry 2312

Spring 1998

Dr. James E. Hanson Lecture: MWF 11:00-11:50 Science Amph.
322 McNulty M 4:30-5:20 Corrigan 64
761-9416Laboratory: T or R, 8-1130 AM or 1-4:30 PM
email: hansonja@lanmail.shu.edu McNulty 221 or 223
homepage: http://www.shu.edu/~hansonja/ Office Hours: MW 3:00 - 5:00 PM
or by appointment

Textbooks

Organic Chemistry, 6th edition, T.W.G.Solomons

Organic Chemistry Study Guide 6th edition, Solomons & Fernandez

Organic Experiments, 7th edition, Fieser & Williamson

Supplemental Materials

molecular model kits (recommended, not required)

Objectives

Students who successfully complete this course will learn the structures, nomenclature, and the chemical, physical, and spectroscopic properties of aromatic compounds, carbonyl compounds, amines, and organic compounds of biological significance. They will learn the reactivities of these classes of compounds, and will be able to predict products when given starting materials and to suggest appropriate routes of synthesis. They will understand these reactivities using reaction mechanisms and energetics and simple theories of resonance and electrostatic stabilization. They will apply this knowledge in the laboratory, where they will learn the roles of both synthesis and analysis in organic chemistry. Above all, the successful student will have learned to think synthetically and analytically about problems in organic chemistry, and will not rely solely on rote memorization.

Grading
Examinations 3 x 100 = 300 points
Quizzes100 points
Final Examination 150 points
Laboratory150 points
TOTAL700 points

Policies

Learning organic chemistry requires consistent effort. To encourage and promote this effort, an assignment or quiz will be given about once a week. As the lowest quiz grade will be dropped, there will be no make up quizzes. Three one hour exams will be given during the semester. Each will emphasize the most recent material, but as knowledge gained earlier in the course (and in prior prerequisite courses) may be necessary for understanding the problems, all exams can be considered essentially comprehensive. Exams will be short answer questions and problems, there will be no multiple choice. Exams will be scored and returned within one week. Upon return, the exam scores will be open for discussion for one week. Except for arithmetic mistakes, exams will only be re-scored in their entirety by the instructor: individual problems will not be re-scored. The final exam will be comprehensive. No make up tests will be given. In the event that an exam must be missed due to a documented medical or other legitimate emergency, the 100 point value of that exam will be added to the final exam. Sets of suggested problems from each chapter will be provided by the instructor. These problems should be worked, but will not be collected. Answers to these problems can be found in the study guide.

ACADEMIC DISHONESTY WILL NOT BE TOLERATED. ANY STUDENT FOUND CHEATING ON AN EXAM OR QUIZ OR PLAGIARIZING OR FALSIFYING A LABORATORY NOTEBOOK WILL BE GIVEN A ZERO FOR THAT EXAM, QUIZ, OR LAB. A LETTER DESCRIBING THE OFFENSE WILL THEN BE PLACED IN THAT STUDENTÍS PERMANENT RECORD. A SECOND INFRACTION WILL RESULT IN DISMISSAL FROM THE COURSE AND A FAILING GRADE.

Laboratory

Safety: The laboratory contains many potential hazards and safety must be taken extremely seriously. Failure to observe safe operating procedures will result in expulsion from the laboratory for the day. A second safety violation will result in permanent expulsion and a zero for the laboratory portion of the grade. Appropriate attire is required at all times in the laboratory as part of safe laboratory practices. This begins with safety glasses and includes long pants or skirts. Shorts, bare feet, and open-toed sandals are NOT permitted. Lab coats and gloves are recommended.

Preparation and Notebook Keeping: Preparation is essential for safety and efficiency in the laboratory. No one will be permitted to work in the lab who has not documented their preparation in the laboratory notebook. This pre-lab preparation will be checked at the beginning of each lab period. As is the practice in all industrial and research laboratories, the notebook will be the primary document for the laboratory. (Most students will have learned how to maintain a laboratory notebook in General Chemistry. Those who have not should purchase Writing the Laboratory Notebook by H.M.Kanare, available in the bookstore.) Notebooks will be collected and graded every third or fourth week.

Grading: The grade for the laboratory will be based on the laboratory notebook, performance in the laboratory, and on a written report over the multi-step synthesis. The lab grade will be based approximately 40% on the notebook, approximately 40% on laboratory performance, and about 20% on the written report.

Evaluation

All students who complete all of the quizzes and assignments without errors and who attend and complete all laboratory experiments and submit a complete and satisfactory laboratory notebook, while scoring at least 50% (after renormalization - see below) of the high grade will be assured a minimum grade of C. These students may earn a higher grade based on their performance on the lecture exams, final, and laboratory. All grades will be assigned based on a renormalization protocol. The high grade in the class will be assigned a value of 100% and all other percentages will be calculated from this norm. The scale will be:
A> 90%
B+87.5 - 89.9%
B80.0 - 87.4%
C+77.5 - 79.9%
C70.0 - 77.4%
D+67.5 - 69.9%
D60.0 - 67.4%
F< 60%

Note that since the normalization value (the high score) will not be known until grades for all components of the course are complete, it is difficult to define a grade with any accuracy until the end of the course.

Examinations
Approximate Date Tentative Topics
2/17-2/23chapters 13, 14, 15, 20, 21, 16
4/1-4/8chapters 16-20
5/1-5/6chapters 19, 20, 22-25
FINAL: May 14, 10:45 AM CUMULATIVE

Last day for withdrawal: March 20

Schedule of Lecture Topics

Spectroscopy (Chapter 13)

Review of Aromatic Chemistry (Chapters 14 & 15)

Anilines and Phenols (Chapter 20.8, & Chapter 21)

Carbonyl Compounds (Chapters 16, 17)

Carboxyl Compounds (Chapter 18)

Enolate Chemistry (Chapter 19)

Amines (Chapter 20)

Organic Compounds of Biological Interest (Chapter 22, 23, 24, & 25)

Schedule of Laboratory Experiments

(Schedule subject to adjustment with at least one week's notice.)

Laboratory meets in 221 and 223 McNulty
1/20 & 1/22 No Laboratory
1/27 & 1/29 Check in & Spectroscopy (Experiment 21)
2/3 & 2/5 Spectroscopy (Experiment 19)
2/10 & 2/12 Multi-Step Synthesis (Experiment 25)
2/17 No Tuesday Laboratory
2/19 & 2/24 Multi-Step Synthesis (Experiment 25)
2/26 & 3/3 Multi-Step Synthesis (Experiment 67)
3/5 & 3/17 Enzymatic Reduction (Experiment 64)
3/19 & 3/24 Qualitative Analysis (Experiment 70)
3/26 & 3/31 Qualitative Analysis (Experiment 70)
4/2 & 4/7 Qualitative Analysis (Experiment 70)
4/9No Thursday Laboratory
4/14 & 4/16 Qualitative Analysis (Experiment 70)
4/21 & 4/23 Qualitative Analysis (Experiment 70)
4/28 & 4/30 Qualitative Analysis (Experiment 70)
5/5 & 5/7 Check Out